Nexus Copy Number 10.0 has the next generation MSR algorithm for deriving copy number and allelic events from NGS data. The enhanced algorithm is optimized for NGS panel data where coverage across the genome is uneven, allowing the software to perform well on a variety of NGS data (WES, WGS, tageted panel, and shallow sequencing).
Key Features of Version 10.0:
Our BAM MSR method uses a Hidden Markov Model (HMM) to segment the genome. It does so, using coarse binning in the “backbone” areas to provide copy number base line and large copy number events, as well as fine binning in “target” areas to provide high resolution copy number detection in targeted regions.
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